Disorganization of the germ cell pool leads to primary ovarian insufficiency
نویسندگان
چکیده
منابع مشابه
Primary Ovarian Insufficiency
Primary ovarian insufficiency or premature menopause is one of the stressful problems in women younger than 40, which may cause numerous early or late psychological and physical complications. Failure of germ cell development is associated with complete ovarian insufficiency, while their decreased number is more likely associated with partial ovarian insufficiency, which leads to secondary amen...
متن کاملPrimary Ovarian Insufficiency
From the Integrative Reproductive Medi cine Unit, Intramural Research Program on Reproductive and Adult Endocrinology, National Institute of Child Health and Hu man Development, National Institutes of Health, Bethesda, MD. Address reprint requests to Dr. Nelson at the Integrative Reproductive Medicine Unit, NICHD– Intramural Research Program on Repro ductive and Adult Endocrinology, CRC, Rm....
متن کاملA new approach to primary ovarian insufficiency.
There is a need for a new approach to managing women with primary ovarian insufficiency. This condition is a serious chronic disease that may have far reaching effects on physical and emotional health. An integrative and collaborative approach to management works best. To maintain wellness, most women with primary ovarian insufficiency need to reassess their primary source of meaning and purpos...
متن کاملEtiologies of Primary Ovarian Insufficiency
“I could not stop crying when my doctor told me I was in menopause! I was only 32 years old and married less than year ago! I wondered whether I had done anything wrong. Later I found out that my grandmother, mother and my aunt went through menopause when they were in their 30’s, but we had never talked about these things before. I never expected this would happen to me because everyone in my f...
متن کاملThe Genetics of Non-Syndromic Primary Ovarian Insufficiency: A Systematic Review
Purpose: Several causes for primary ovarian insufficiency have been described, including iatrogenic and environmental factor, viral infections, chronic disease as well as genetic alterations. Given the large number of genes described in the literature so far, the aim of this review was to collect all the genetic mutations associated with non-syndromic primary ovarian insufficiency. Methods: All...
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ژورنال
عنوان ژورنال: Reproduction
سال: 2017
ISSN: 1470-1626,1741-7899
DOI: 10.1530/rep-17-0015